name
Kononenko Vladimir Ivanovich
Scholastic degree
•
Academic rank
associated professor
Honorary rank
—
Organization, job position
• Rostov state medical university
заведующий кафедрой стоматологии №3
Research interests
онкология, хирургия, стоматология
Web site url
—
Current rating (overall rating of articles)
0
TOP5 co-authors
Articles count: 1
Сформировать список работ, опубликованных в Научном журнале КубГАУ
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Description
While studying the content of hypoxia-inducible factor 1-alpha and vascular endothelial growth factor in the tumor tissue, oral fluid and peripheral blood of 141 patients with oral mucosa cancer T1-3N0-2M0, it was shown that the development of purulent inflammatory postoperative complications in patients with oral mucosa cancer is associated with an increased expression of HIF-1α in the tissue and its translocation from the cytoplasm to the nucleus, activation of the neoangiogenesis processes. It is informative to determine HIF-1α factor in the blood serum, which, for further development, can be used as a non-invasive diagnostic marker to predict the postoperative course in this category of patients
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