14.00.00 Medical sciences
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THE REGULATORY-ADAPTIVE STATUS OF WOMEN WITH DIABETES AT 37 - 38 WEEKS OF PREGNANCY
DescriptionRegulatory-adaptive status of pregnant women with diabetes should be considered at the solution of the delivery
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Description
The research shows the possibility of extended preimplantation genetic screening (PGD) that allows to improve the strategy of selection of embryos that satisfies not only the requirement of the absence of chromosomal abnormalities, but also includes their additional check for predisposition to various diseases, as well as the choice of the embryo with the most optimal HLA haplotype in cases with expressed compatibility of parents for HLA-genes
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LEVEL OF MOTIVATION OF CREW FOR FIRST AID TREATMENT ON SHIPS OF COMMERCIAL FLEET
DescriptionThe results of the questionnaire survey of cadets of Maritime University, Maritime College and students who had been given training in the Institution of Advanced Training are presented. It is revealed that the level of motivation of ship personnel for first aid treatment to victims on commercial ships is two times lower than that of cadets. The conclusion about the necessity of solution the legal aspects of sailorsparamedics, working under the Russian flag was made
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Description
Pathology of digestive organs is high on the list in structure of diseases of children and teenagers. Now many pediatricians face that teenagers at the same time have several diseases. The most exact method of detection of the available pathology is medical examination. These inspections of rural teenagers with chronic gastroenterological pathology are given in article. The carried-out work allowed revealing the main features of a state of health of this contingent
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THE MATHEMATICALLY BASED CHOISE OF VISCOELASTIC IN SHUNT GLAUCOMA SURGERY
DescriptionThe dramatic lowering of intraocular pressure (hypotony) is developing during glaucomatous surgery due to the formation of the new aqueous humor outflow. The calculations of the flow in the fluid balance parameters have shown, that for the normal intraocular pressure maintenance in the postoperative period the fluid flow out of the anterior chamber should not exceed 0,04 microliter in minute. The intensity of the aqueous humor outflow through the shunts with different parameters does not depend on the shunt length. The shunt with the inner hole radius 0,025 mm is the most safe as it provide the less outflow. The experimental comparative study of the static viscosity of the most widely used viscoelastics in ophthalmological surgery was carried out. It was stated that used in eye surgery viscoelastics on the basis of 1%, 2% and 3% sodium hyaluronate possess the viscosity, that differs in 10 and 100 times and has significant influence on the flow intensity out of the anterior chamber when the new outflow tracts are formed. The mathematically based choice of the most optimal relationship between the viscoelastics physical parameters and the inner hole size of the shunt type glaucoma drainage devices was established. Shunt with the inner hole radius 0,05 mm and simultaneous use of 2% and 3% sodium hyaluronate solution is the most safe for the maintenance of the eye tonus during the first 5 days after glaucoma surgery. The presented correlation allows to increase the safety of the surgical treatment of the patients with the refractory glaucoma
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Description
Isolation of fetal cells from the blood of a pregnant woman is more relevant for receiving the information of the genome of a fetus and implementation in clinical practice, non-invasive screening methods for prenatal diagnosis. The work proposes efficient ways of sorting trophoblasts circulating in maternal blood for the diagnosis of fetal aneuploidy in early gestation by analyzing microsatellite marker of the chromosomes that most prone to numerical aberrations (13, 18, 21, X and Y). A set of microsatellite markers allowed to reveal aneuploidy in three pregnant women, and also to exclude mosaicism and contamination of samples with maternal cells. A retrospective analysis of data on invasive cytogenetic studies (chorionic villus sampling) confirmed the results of the study
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Description
The aim of this work: a study of health - social and ethical aspects of health care workers in the framework of the prevention of a healthy lifestyle among youth. To study the level of students' knowledge about HIV prevention and detection of bad habits - drinking, smoking, drug addiction, a study author profiles. We have used empirical, sociological and statistical methods
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EVALUATION LABILITY OF THE VISUAL ANALYZER IN THE TEST OF CARDIORESPIRATORY SYNCHRONISM
DescriptionThe article presents the evaluation of the lability of the visual analyzer among healthy individuals and patients with lesion after a stroke in the occipital cortex, temporal and parietal lobes
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TRANSCRIPTOMIC ACTIVITY OF ESTROGEN-REGULATORY GENES IN MALIGNANCY UTERINE TISSUES
DescriptionUterine cancer is the sixth on prevalence of cancer among women in developed countries. Hyper-estrogen level by endogenous or exogenous origin plays the leading role in this disease pathogenesis. This study purpose was investigating the expression of genetic loci responsible for the estrogen reception and metabolism to better understanding of the molecular mechanisms of uterine tissues malignancy. We investigated the relative expression of genes (CYP1A 1, CYP1A 2, CYP1B 1, CYP19A, ESR1, ESR2, GPER, STS, SULT1A and SULT1E1) by real-time PCR in tumor and conditionally healthy uterine tissues of 27 female patients in Southern Russia aged 38-72 years with histologically confirmed diagnosis of uterine cancer. It is found that transcription activity of these genes during malignancy of uterine tissues depends of female patients age and the stage of tumor cells differentiation. It is found that malignancy change in the transcriptional activity of investigated genes in uterine tissue depends of patients age and stage of tumor cells differentiation. Particularly, it was found, that changes of gene transcription balance of enzymes that provide sulfation and hydrolysis of steroid sulfates is depending of patient age and the degree of tumor cells differentiation. In addition, the sinking of gene expression of nuclear estrogen receptor ESR1 as lowering cell differentiation of tumor tissues. We have also shown gene expression of nuclear estrogen receptor ESR1 decline as lowering cell differentiation of tumor tissues
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VAGINAL MICROECOLOGY IN WOMEN WITH METABOLIC SYNDROME IN CLIMACTERIC PERIOD
DescriptionThe aim of the research is to study the peculiarities of vaginal microbiocenosis in female patients with metabolic syndrome during peri- and postmenopause. 320 women in the climacteric period aged of 45-70 were examined. Two groups were formed: the main group (160 female patients with metabolic syndrome), the control group (160 women without metabolic syndrome). The average age of women 54.5 ± 7.2 years. Depending on the length of menopause each of the two groups was divided into three subgroups.Microscopy of vaginal smears, the colpocytological analysis, the culture test of vaginal discharge were conducted. The statistical processing of the results was carried out with the help of programme sets Microsoft Office 2010 (MicrosoftExcel) and «STATISTICA® for Windows 6.0». A tendency of decreasing frequency of non-specific vaginitis with aging and of increasing frequency of vaginal atrophy, disorders of vaginal biocenosis (lactobacillus deficiency and the domination of conditionally pathogenic microorganisms) was discovered. The frequency of vaginal atrophy in women with a length of postmenopause of 10 years and older was 65.9% in the subgroup of in female patients with metabolic syndrome and 63.6% in the subgroup of female patients patients without it. The more observable changes in vaginal biotope were found in women with metabolic syndrome