South Federal University
Author list of organization
List of articles written by the authors of the organization
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CLINICAL AND MORPHOLOGICAL FACTORS AND PREDICTION PARAMETERS OF CELL CYCLE IN ESOPHAGEAL CANCER
DescriptionThe aim of the study is to compare the traditional clinicopathologic factors and prognosis of cell cycle parameters, such as ploidy, cell cycle kinetics, as well as the study of DNA content in the tumor tissue of patients with esophageal cancer. Cancer of the esophagus - a very aggressive malignant disease, most commonly manifested impaired swallowing. As a rule, this type of cancer pathology is characterized by unfavorable outcome. Ploidy and cell proliferation activity, defined by the content of the DNA of the tumor - synthesizing cells are one of the important indicators of the growth rate of malignancy and prognosis. The study was performed on tumor tissue fragments of the 30 patients operated on for cancer of the esophagus. DNA study - conducted in the open cell material aftercare. DNA cell content was determined by flow cytometry BD FACSCanto II. By studying the DNA-cytometric parameters, we found the prevalence of aneuploid tumors in 66.7%. It was shown that DNAcytometric parameters are independent of gender. Major weight of diploid and aneuploid cell tumors of the esophagus was in G0 / 1 phase of the cell cycle. Comparative analysis of DNA - cytometric parameters and the degree of differentiation of esophageal tumor revealed a prevalence of aneuploid tumors in all the test cases. content distribution pattern of tumor cells was found in the G0 / G1-, G2 + M -, S - phase of the cell cycle at different stages of the disease
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Description
Mortality from malignant diseases is directly linked to early metastasis and relapse. It is now possible to identify individual tumor cells in bone marrow biopsies and peripheral blood. Colorectal cancer is one of the leading places in the structure of cancer incidence and mortality, both in Russia and around the world. Studies have shown that after surgery the ability of tumor cells to the dissemination and implantation increases. The work contains 30 patients with the verified colorectal cancer with metastasis to the liver. To determine the CSC we have applied an analysis technology in CellSearch System ™ (Janssen Diagnostics, LLC). Our study of the number and frequency of detection of circulating tumor cells in peripheral blood of patients and control group demonstrates the reduction in the number of CTCs during laparoscopic surgery and changing the dynamics of the level of tumor cells in the form of reduction from the stage of the mobilization of the drug due to minimally invasive access, minimizing manipulation in the projection of the tumor and as a consequence, preventing the release into the blood stream of single tumor cells
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HIFU: PROSPECTS OF APPLICATION IN ONCOUROLOGY
DescriptionProstate cancer (PC) is one of the most frequently malignant neoplasms in the worldwide male population. Back in the 90's began a promising noninvasive method of high-intensity focused ultrasound (HIFU) as an alternative to radical prostatectomy for the treatment of localized prostate cancer was used. Information about the destructive histological effect by HIFU has been known since the 1930, however, the clinical implementation of this technology due to the absence at the time visualization capabilities for monitoring during the procedure has been postponed. In this paper, an overview of published data on the HIFU clinical application in prostate cancer as a major, "saving" and focal therapy. Examples of a favorable combination of this method are also provided with pharmacological agents. Based on the analysis of clinical data, we can say that HIFU is a good alternative minimally invasive therapeutic modality for patients with prostate cancer who are not candidates for radical prostatectomy. Applying of HIFU is possible as a treatment option with local recurrence after external radiotherapy, with careful selection of patients is important, depending on prognostic factors
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Description
In the article we have stated results of the monitoring of local populations of rare plans species in the territory of the nature monument (NM) of the Rostov region «Raznotravno-tipchakovo-kovylnaya steppe» (Zernogradsky district). Vegetation of NM belongs to the poor version of the Azov steppe, flora contains 291 species, including 13 rare species (Astragalus ponticus Pall., Bellevalia sarmatica (Pall. ex Georgi) Woronow, Calophaca wolgarica (L. f.) DC., Caragana scythica (Kom.) Pojark., Centaurea talievii Kleop., Crambe pinnatifida R. Br., C. tataria Sebeok, Crocus reticulatus Stev. ex Adam, Eriosуnaphe longifolia (Fisch. ex Spreng.) DC., Iris pumila L., Stipa pulcherrima К. Koch, S. ucrainica P. Smirn., Tulipa schrenkii Regel), included in the Red List of the Rostov region, including 6 species included in the Red List of the Russian Federation. In 2016 were specified the patterns of rare species distribution in NM borders, and also other important parameters of their populations (number, density, age structure, etc.). The group of rare plants species, included in the Red List of the Rostov region, in the territory of NM includes 65 % of their total number known in Zernogradsky district. The special sozological value of NM is determined by the large local populations of Calophaca wolgarica, Astragalus ponticus and Crambe pinnatifida. Local populations of all rare species in the territory of NM can be considered to be steady as inhabit here during last 50 years
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06.00.00 Agricultural sciences
DescriptionThe article describes the results of studies on elemental composition of corn grain under various fertilizer treatments. The balanced application of fertilizers is an important factor in optimizing corn nutrition on ordinary black soils and obtaining ecologically safe and clean crop production
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THE ROLE OF QUANTUM ENTANGLEMENT IN TASKS OF THE GAMES THEORY
01.00.00 Physical-mathematical sciences
DescriptionThis article discusses an economic game called "The struggle for markets". We have generated a mathematical model of quantum realization of this game. For clarity, the algorithms are derived for soft and hard quantum games for assessing the impact of the degree of entanglement to work and the result of the algorithm. There are step-by-step instructions for the sequence of actions and operations to create a quantum model of the game. The aim is to assess the influence of the degree of entanglement on work algorithms. Also, we investigate the influence of quantum entanglement on the win for two or more players. The article gives a comparison with classical results
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SIMULATION OF QUANTUM COMPUTING USING HARDWARE CORES
DescriptionThis article discusses the principles of quantum computing simulation using hardware approach. We describe a general mathematical model of a quantum computer; we show the method of mathematical modeling of quantum computation with optimization and a scheme of a hardware processing core in a quantum computing accelerator. The article gives a method of assessment of increasing productivity in the simulation of quantum computations using computing hardware core. The problems associated with the parallelization of computations on a hardware accelerator, simulating quantum computing were analyzed. The work lists the results of comparison of software and hardware simulation, as well as the dependence of the temporal evaluation of the number of qubits and parallel ALU in the computer-hardware accelerator
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LOGICAL PRICE ESTIMATION OF THE RUSSIAN FEDERATION EDUCATIONAL LANDSCAPE
DescriptionIn the given article, we describe an approach to the formation of learning environment optimal structure based on logical price tools using through statistical assessment of universities rank distribution. The actuality of this approach is based on the analysis of modern methods to the formation of the university landscape and assessment of a number of systemic problems of universities’ structure transformation, which consists in the disproportion reinforcement and reducing the variety of educational programmes and research schools, which prevents its effective development. The postulates of institutional university transformations based on the pragmatic paradigms providing stability and progressive development of the system in its self-development and evolution process are proposed as a methodological concept of using the statements of the cenoses theory. The logical price analysis of the Russian universities structure in 2015 conducted above has confirmed the proposed hypotheses, showing statistical coupling of university environment elements, their relatively systematic instability and structural imbalances. The educational system assessment as a cenosis allowed to reveal points of the required impact factor, state intervention direction in the distribution structuring, possible limitations associated with the implementation of large universities support programmes. The proposed approach has a high level of reality objective assessment and may be used when making long-term strategic decisions
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10.00.00 Philological sciences
DescriptionThe article discusses the results of the pragmalinguistic experiment. Since language game is a result of speech creative work, which manifests the individuality of a linguistic personality, the politician can intentionally use language game and thereby consciously form his attractive image. The politician, who uses different kinds of language game, makes some personal characteristics building up the portrait aspect of effective political image more distinguished and thus affects the election decision of the voter. It has been studied whether language game influences such characteristics as determination, insistence, persuasiveness, emotionality, confidence, energy, sense of responsibility, dedication, trustworthiness, honesty, a certain hardness, decisiveness, autonomy, adherence to principles and assertiveness. It has been concluded that language game influences 11 of the 15 characteristics, this fact confirms the hypothesis
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COGNITIVE MODELING OF THE IMPACT OF SELF-ORGANIZATION FACTORS ON THE ENTERPRISE SUSTAINABILITY
DescriptionThis article discusses the problem of methodological support for the management of the recovery cycle of Russian industry, which is caused by the transformation of factors affecting the achievement of the required parameters of competitiveness. Given the low level of technological development, it is proposed to rely on the concept of sustainability in determining the strategy of re-industrialization in Russia. As a theoretical platform of such a concept, the ideas of intellectualization of enterprise management are proposed, which were developed in the foreign theory of industrial management. Thus, the main factors influencing the stability of the enterprise were correlated with elements of the "ADACOR holonic" -architecture of management, inspired by biological and evolutionary theories. An empirical analysis of the impact of self-organizing factors using the technology of cognitive modeling, which revealed a significant impact on the company's sustainability of environmental assessment factors. The state is revealed under which the effect of local stability within the limits of the parameters "Diagnostics of threats" and "Unpredictability of the environment" is achieved, which makes it possible to form a complex of management actions to regulate these parameters using the coenoses tools. The proposed interdisciplinary approach, based on a system of regularities of the physical and mathematical order, will greatly enhance the effectiveness of forecasting and the predictability of enterprise development