№ 133(9), November, 2017
Public date: 30.11.2017
Archive of journal: Articles count 94, 254 kb
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DESIGN OF THERAPEUTIC PHAGE COCKTAILS BASED ON T4-TYPE BACTERIOPHAGES: ADVANTAGES AND DISADVANTAGES
DescriptionIn the review, the stages of designing therapeutic cocktails of T4 type bacteriophages based on works by Harald Brüssow from Nestlé S.A. (Switzerland) are considered. The main stages of this process are identified: analysis of existing cocktails, selection of phages; creating a collection; cultivation of the host bacterium, multiplication of viruses; purification of the preparation; contamination testing; preservation, stabilization and storage; preclinical and clinical trials. H. Brüssow first studied the Russian drug " Coli-Proteus bacteriophage " of "Microgen" with the help of metagenomic analysis, electron microscopy and conducted its clinical studies. Prof. Brüssow considered the advantages of T4 bacteriophages for the treatment of Escherichia coli infections. Researchers studied methods of cultivation in Erlenmeyer flasks, in a bioreactor, in disposable sack cultivators for the propagation of viruses. For its purification the chromatography, centrifugation, filtration and polyethylene glycol precipitation were studied. To quickly check the contamination of phage cocktails, a mass spectrometry method is proposed. Researchers considered basic strategies, such as lyophilization, spray drying, the formation of microcrystals and microspheres to stabilize the preparations. They also reviewed the results of clinical trials of phage cocktails. We have listed the problems of selecting T4 bacteriophages from the point of view of modern knowledge. H. Brüssow and his colleagues carried out an interesting work on the construction of phage cocktails based on T4 type bacteriophages, and also revealed the problems of the current state of phage therapy
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IMPACT OF INTEREST CENTRAL BANK POLICY ON DEPOSIT POLICY OF COMMERCIAL BANKS
DescriptionThe article is devoted to the evaluation of the influence of the interest rate policy of the central bank (CB) on the deposit policy of commercial banks. The author analyzes the dynamics of the Central Bank's key interest rate, weighted average interest rates to individuals funds obtained raised by credit organizations. Particular attention was paid to regression analysis to determine the dependence of rates on deposits of individuals from the Central Bank's key rate. The authors presented the forecasted values of interest rates on deposits of individuals, which clearly demonstrate the current situation of the deposit policy of commercial banks. A number of indicators that affect the change in interest rates on deposits of individuals are considered. In addition, the main positions on improving the deposit policy are presented. The conclusion is drawn that interest rates on deposits depend on a whole spectrum of both external and inner banking components. Each bank develops its own deposit policy, determining the terms, types of deposits and their interest, terms of conducting deposit operations, relying on the specifics of their activities and taking into account the factor of competition with other banks and the inflationary processes that occur in the economy
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Description
The article attempts to study the participation of student of the Chechen-Ingush state pedagogical / teacher training Institute A. N. Medina in the great Patriotic war of 1941-1945, to gather biographical information about him
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Description
Under consideration is the international experience of NCFU in developing student mobility via French resource center. Today, in the era of globalization, student academic mobility is the integral part of the process of integrating higher education establishment into common European educational framework. Emphasis is made on the academic environment as an important factor of realizing international student mobility. Tendencies towards open academic environments set up new possibilities for academic exchanges both with foreign and Russian – based academic establishments. Thus, we can talk both about inner and outer student and teacher mobility, which is realized individually as well as on the institutional level. Conclusion is made that academic exchanges can be viewed upon as means of developing and renewing higher school educational programmers in Russia. This can eliminate exclusiveness of Russian educational system; pave the way for obtaining recognition of its educational programs; secure transparency and acknowledgment of competences and qualifications to raise student mobility and competition of Russian educational programs in the world market of educational services. The experience of NCFU in developing international activity discussed in the article illustrates the theoretical base of the research because empiric data well integrates into the framework of academic mobility
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THE FUNCTIONS OF PROPER NAMES IN LANGUAGE FOR SPECIAL PURPOSES (LSP)
10.00.00 Philological sciences
DescriptionIn any language there are such lexico-grammatical categories of nouns as proper names and common names. This fact is explained with the speaker’s desire to differentiate homogeneous subjects to individual and unique subjects. Both has their own purpose. Functions and aims. Being one of the subsystem of national language, language for special purposes provides the professional communication of people in scientific, production and technical spheres. But compare with a common language, language for special purposes is more laconic and is limited with lexis of researched scientific part. A common language in a process of communication transfer intellectual and emotional information; in fiction there is also esthetic information, but language for special purposes transfer only intellectual information. So synonyms, homonyms and tropes are strange for language for special purposes. Naturally, the forms of Proper names and their role are restricted. The emotional sphere depends on the approval of the author (denotate). So, the emotions and estimation depend on the content not a form of the language
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THE DEVELOPMENT OF A DISTANCE COURSE IN THE MOODLE EDUCATIONAL ENVIRONMENT
DescriptionPresently, the problem of carrying into effect of distance technologies in higher education is becoming more urgent. The article analyzes various software products with the help of which a distance course can be developed, and the stages of its development are described. The choice of modular object-oriented dynamic learning environment Moodle as a system for organizing distance courses in higher education is founded. There are described not only the advantages of Moodle learning environment, but also the drawback which is connected with the impossibility to identify a user that requires additional use of information technologies. There are also regarded the methodical and technical features of the distance learning course development in this learning environment. A particular attention is paid to the interactive coordination of the teacher and students, which is realized by creating a chat or forum for convenient and fast exchange of messages between users, besides, the teacher has the possibility to monitor the work of students not only offering control and test tasks, but also determining the deadline for the assignment to be fulfilled, the possibility of a repeated access to correct errors. There is presented the experience of developing a distance course in the Moodle study environment at the Priamursky State University for the discipline "Theory of Probability and Mathematical Statistics"
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PROBLEMS OF RESTORATION OF NATIONAL AUTONOMIES OF REPRESSED PEOPLES
DescriptionThe article attempts to highlight the problems of restoring the autonomies of the repressed peoples of Russia during the Great Patriotic War. Karachais, Kalmyks, Chechens, Ingush, Balkars and other peoples were forcibly relocated to the eastern regions of the country, and their autonomies were abolished. And only after the death of Stalin began the process of softening the special settlement regime for deported peoples. However, the decisive role was played by the 20th Congress of the Party, held in February 1956. At a closed meeting of the congress, the eviction of peoples, NS. Khrushchev called "a gross violation of the national policy of the Soviet state." The Twentieth Party Congress proposed reviving the illegally abolished national autonomies of repressed peoples. Public condemnation of mass repressions against the peoples of the North Caucasus was of great importance for the fate of deported ethnic groups, facilitated a number of measures to restore justice
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22.00.00 Sociological sciences
DescriptionModern representations of threpsology demonstrate importance of harmonization of eating which consists in providing an organism with all necessary feed elements in full and energy in the corresponding quantities and ratios. The causes of obesity and measures against it, sedentary lifestyle and diseases associated with these factors. Social significance of the problem evidence of the need to combat the spread of obesity. It is established that since 1975 the number of people suffering from obesity worldwide has increased more than three times; more than 1.9 billion adults, 18 years and older were overweight, of which over 650 million people were obese; 39 % of adults 18 years and older, were overweight, and 13% were obese. The situation with obesity in the CIS countries is ambiguous. In the post-Soviet space, the situation with obesity in adults and children gradually becomes threatening. Domestic and foreign experience indicate that the most accessible and economically feasible method of correcting the nutrition and health of the population is the inclusion in the diet of modern man healthy food, having direct functional properties
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THE DEVELOPMENT OF DESIGN THINKING OF BACHELORS AS A WAY OF PROFESSIONAL COMPETENCES FORMATION
DescriptionThe article reveals the problem of inconsistency of modern professional education structure of the labor market needs. The considered possibility of formation of professional competence of bachelors of design through the development of personal qualities in the design activity. The authors propose a solution to the problem, which is to focus University education on the formation of the model competence designer. The concept design represents the art and design work based on advanced design thinking, which is based on creative thinking and practical skills, backed up by self-organization of personality. Competence includes knowledge, skills, abilities, personal qualities and under certain conditions, these categories may be considered from the standpoint of professional competence. The authors mean by the methods of formation of professional competence of certain techniques and ways of interacting of the teacher and the bachelors of design in project activities that conform to the competence approach in education aimed at the formation and development of social, communicative, professional and other qualities of the person. This allows students more fully realized in modern socio-economic conditions. In the modern educational process by preparation of bachelors of design the authors identify methods of activization of educational activity, organization of independent work and research activity of students, as most conducive to the formation of common cultural and professional competences of future designers
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CALCULATION OF MELTING RATE OF DEBRIS-COVERED AREAS OF A MOUNTAIN GLACIER
DescriptionConsiderable parts of the ablation zones of mountain glaciers in various mountain systems of the World are covered with rocks (dibris). Heat and physical properties of debris layer are very different from those of ice. Debris layer determines ablation rate and ice run-off regime. Dependently on thickness, it can accelerate ablation or totally isolate ice cover from melting. To describe ablation rate in a mathematical model correctly, one needs to include in it a block responsible for heat exchange of debris-covered areas with the atmosphere. In the paper, we consider an algorithm for calculation of ablation rate under the layer of debris, which is to be incorporated to the surface mass balance model. We also describe results of calculations of temperature distribution in a debris layer and estimates of ablation rate under the latter. All calculations were carried out for heat and physical properties of Djankuat Glacier in the Central Caucasus